ANTHROPOMETRICS, % PREDICTED FORCED VITAL CAPACITY (%FVC), AND IMPAIRED GLUCOSE TOLERANCE (IGT) IN CYSTIC FIBROSIS (CF)

Forced Vital Capacity (FVC) and Forced Vital Capacity in 1 Second (FEV1) of Apparently Healthy Non-smoker Adult Obese

Glucose tolerance in cystic fibrosis.

Glucose tolerance was evaluated in 356 living and dead patients with cystic fibrosis who were recorded at the Danish Cystic Fibrosis Centre. Twenty two patients (6%) were treated elsewhere, 25 (7%) were unable, unwilling or too young (age less than 2 years) to participate; 309 patients (87%) were therefore eligible for the study of whom 99 (32%) were dead and 210 (68%) were alive. Of the dead p...

Insulin-secretion abnormalities and clinical deterioration related to impaired glucose tolerance in cystic fibrosis.

OBJECTIVE To evaluate insulin-secretion kinetics and insulin sensitivity in cystic fibrosis (CF) patients with normal glucose tolerance (CF-NGT), impaired glucose tolerance (CF-IGT) or CF-related diabetes (CFRD), and the potential effects of moderate hyperglycemia on clinical and nutritional status. DESIGN AND METHODS Cross-sectional study including 50 outpatients with CF. Patients underwent ...

Insulin Resistance (IR) in Impaired Glucose Tolerance (IGT)

Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes mellitus was described as an early pathogenetic phenomenon[1]. Moreover, impaired action of insulin (insulin resistance) has been associated with pre-diabetic state, impaired glucose tolerance and diabetes mellitus[2]. It is postulated that IR then leads to insulin deficiency. Thus, glucose into...

Impaired Fasting Glucose in Cystic Fibrosis

OBJECTIVE While glucose tolerance abnormalities are common in cystic fibrosis (CF), impaired fasting glucose (IFG) has scarcely been explored. No studies have examined the relation between IFG and clinical status. RESEARCH DESIGN AND METHODS Data were retrieved from the University of Minnesota CF database on oral glucose tolerance tests (OGTTs) performed in 1996-2005. Subjects were identified...